Since you didn't reply, I will assume that it denotes the symmetric difference A⊕B=(A∪B)−(A∩B).
First, C−B is just the collection of elements in C that is not in B, i.e., C−B={2,4}.
Now, we calculate A⊕(C−B)=A⊕{2,4}.
Note that A∩{2,4}=∅ since the two sets do not have common elements. Then A⊕{2,4}=A∪{2,4}={1,2,4,5,6,8}.
Hence, we have A⊕(C−B)={1,2,4,5,6,8}.