What is 450 times 80 minus ten plus 180 times 66 divide by 4?

Here's what you have written:

450 X 80 - 10 + 180 X 66 / 4

We always perform the multiplications and/or divisions as we encounter them from left to right as we encounter them.

So 450 X 80 =36000

The next thing we would evaluate is 180 X 66 = 11880

Then, we would divide this by 4 = 2970

So we have

36000 - 10 + 2970 = 38960